At the first annual CMF conference we discussed Prozac. This seems to be the scariest drug for most parents. Today I wanted to discuss the timing of research, and Prozac is an excellent example.
In April of 2006 a study was published "Fluoxetine Rescues Deficient Neurogenesis in Hippocampus of the Ts65Dn Mouse Model for Down Syndrome". The study gave fluoxetine (which is generic Prozac) to the DS mouse and then examined the memory and learning area of the brain (which is called the hippocampus) 3 weeks later. Within 3 weeks, the brain had formed twice the number of nerves than before. Notice the title of the study, "...Rescues Deficient Neurogenesis...". This tells us that we know people with Down syndrome are naturally deficient at growing new neurons on their own, without some kind of help.
Back to timing. A second study, that looked at learning and memory in the Down syndrome mouse, concluded that after being treated with Prozac the mice had a "complete recovery of memory performance". Aren't these the kind of conclusions we want? Do you know when that study was published?
June of 2010
It took 4 years from one study to the next! Wow !!
Do we believe these studies and move forward and treat with a drug that has been on the market for 30 years, or do we wait 4 more years?